Role of MCC/Eisosome in Fungal Lipid Homeostasis
One of the best characterized fungal membrane microdomains is the MCC/eisosome.The MCC (membrane compartment of Can1) is an evolutionarily conserved ergosterol-rich plasma membrane domain.It is stabilized on its cytosolic face by the eisosome, a hemitubular protein complex composed of Bin/Amphiphysin/Rvs (BAR) domain-containing Pil1 and Lsp1.These